Best Medicine Renewed for a Second Season by FOX
FOX has announced that its breakout hit series Best Medicine has been renewed for a 12-episode second season to debut in the 2026-2027 season.
“Best Medicine quickly became a breakout for us this season, blending sharp humor with real heart,” said Michael Thorn, President of FOX Television Network. “Liz Tuccillo brings a distinctive creative voice to the series, and Josh Charles leads an exceptional cast that audiences have embraced. We, along with Propagate, are excited to build on that momentum in Season Two.”
The series premiere of Best Medicine delivered 12.6 million total multiplatform viewers, and the series ranks among broadcast’s Top 2 highest-rated drama debuts this season among Adults 18-49, alongside its fellow FOX freshman series Memory of a Killer, starring Patrick Dempsey.
Best Medicine currently stands as FOX‘s second-largest 7-day total multiplatform audience of the season to date, averaging 6.0 million P2+ viewers across its first five episodes. Each of those initial telecasts surpassed one million viewers in 7-day streaming.
Best Medicine stars Emmy Award nominee Josh Charles, Abigail Spencer, Josh Segarra, Annie Potts, and Cree.
The series is produced by FOX Entertainment Studios and executive produced by Ben Silverman, Rodney Ferrell, Howard T. Owens, Mark Crowdy, and Philippa Braithwaite. Liz Tuccillo serves as both executive producer and showrunner.
Based on All3Media International’s successful format Doc Martin, originally produced in the U.K. by Buffalo Pictures in association with Homerun Film Productions, and brought to American audiences by Propagate Content. Best Medicine is distributed worldwide by FOX Entertainment Global.
The series centers on Dr. Martin Best (Josh Charles), a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child with his Aunt Sarah (Annie Potts).
There, he encounters an eclectic group of townspeople, including schoolteacher Louisa Gavin (Abigail Spencer), Sheriff Mark Mylow (Josh Segarra), and his assistant Elaine Denton (Cree).
Martin’s blunt, no-nonsense bedside manner quickly alienates the quirky locals, even though he is the only doctor they have. While he can expertly diagnose any medical mystery, he struggles with a debilitating new phobia and childhood trauma that make intimacy difficult.
In a town defined by tenacity and heart, the very people Martin pushes away may ultimately be exactly what he needs. Best Medicine airs Tuesdays (8:00-9:00 pm ET/PT) on FOX, and is available the next day on Hulu.
An all-new episode airs Tuesday, March 3 (8:00-9:00 pm ET/PT), in which BAFTA Award-winning actor Martin Clunes, the original star of the UK’s Doc Martin, guest stars as Martin’s father, Robert Best, joined by Judith Ivey as his wife, Vanessa. When Martin’s parents make a surprise visit, he suspects his father may be hiding a serious health condition, forcing the two doctors to operate together while navigating long-simmering family tensions.
